Letter to Editor

As authors and readers alike, we appreciate the important discussion on disclosure and transparency that followed our recent publication in JVIM. We especially appreciate the chance to respond within a considerate environment, like a letter to the editor. Briefly, we believe that issues of perceived bias should be addressed by full disclosure and transparency. With regard to Dr Moore's letter, his main stated concern was the fact that two of the five pages of the published version of our article were devoted to a single product. We believe that this was appropriate for several reasons: (1) the stated intent of the review was to highlight novel formulations suitable for use in the dog; (2) in judging how content is allocated to different parts of a review, beyond simple page numbers, it is perhaps more reasonable and fair to consider the evidence related to a specific subject. Based on the fact that references of the highest levels of evidence were related to one product (Paccal), including a multi-center random-ized placebo-controlled blinded study, we believe that the number of pages allocated to Paccal was justifiable and not a reflection of bias; and (3) throughout the review process, considerable interest was expressed by the reviewers to more directly summarize information from these noteworthy high evidence references rather than simply referring readers to the references. We agreed to these requests of the reviewers and this added to the content of the Paccal section. In retrospect, we stand by and agree with the recommendations generated by this independent peer review. Accordingly, we disagree with the suggestion that Paccal was unduly emphasized. As investigated and cited by Dr Moore, the author disclosures for this manuscript included the following: Dr Vail was a paid consultant of Abbott and Oasmia at the time of manuscript preparation and disclosure, and accordingly he made the appropriate disclosure of both of these relationships; Dr Khanna was a paid consultant of Abbott at the time of manuscript preparation and disclosure, and accordingly made the appropriate disclosure of that relationship; Dr Khanna was not a consultant of Oasmia during manuscript preparation or at the time of disclosure; Dr Khanna had a past relationship with Oasmia and that relationship was disclosed at the time it was active during earlier publications and presentations related to Paccal; Dr Rosenberg was a consultant of Abbott and Abaxis during manuscript preparation and at the time of disclosure; Dr …